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Why neural models succeed even when they're secretly wrong

Houman Safaai, Bernardo L. Sabatini

June 1, 2026

Researchers tested whether successful predictions by simplified neural models—ones that assume inputs act independently—actually reveal how neurons compute. Using maximum-entropy models and hippocampal recordings, they found that these simple models can absorb hidden complexity into their fitted parameters through a phenomenon called feature leakage. A neuron with genuinely nonlinear computations can masquerade as a linear one if you measure it under the right conditions. The distinction matters: prediction accuracy alone doesn't tell you the mechanism.
Published as Feature leakage and the identifiability of direct-dependency entropy models of neural activity arXiv:2606.01661
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