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Psychosis doesn't break the brain's scaling—it just shifts it
Irem Topal, Paola Moreno Ancalmo, Guillermo Montana Valverde, Philipp Homan, Wolfram Hinzen
June 4, 2026
Brain activity in healthy people follows scale-invariant patterns—think of fractals repeating at different magnifications—that support efficient communication. Using three complementary analysis methods on resting-state fMRI, the team found early psychosis patients maintain this scale-invariant organization but with shifted parameters across multiple measures. This suggests psychosis involves a recalibration of collective brain dynamics rather than a loss of critical-like behavior.
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