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q-bio.PE

Why standard biology models fail during system transitions

Pan-Jun Kim

May 27, 2026

Biologists often assume fast molecular processes instantly reach equilibrium, letting them ignore relaxation delays and focus only on slow dynamics. But near transition points—where systems flip between states—this shortcut crumbles. This work shows the overlooked relaxation effects actually shape when oscillations begin and how long state changes take, with surprising time-delay effects that standard models miss entirely.
Published as Widespread quasi-steady state assumption in biological interaction modeling mischaracterizes system transitions arXiv:2605.28652
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